教育经历
| 入学时间 |
毕业时间 |
学位授予单位 |
学历 |
| 2003-09-01 |
2006-06-30 |
华中农业大学 |
博士研究生毕业 |
| 1997-09-01 |
2000-06-28 |
华中农业大学 |
硕士研究生毕业 |
| 1993-09-01 |
1997-06-25 |
华中农业大学 |
大学本科毕业 |
工作经历
| 起始年月 |
截止年月 |
所在单位名称 |
| 2021-05-01 |
至今 |
北京化工大学 |
| 2011-10-03 |
2012-10-05 |
佛罗里达大学 |
| 2007-11-09 |
2011-09-30 |
中国科学院微生物研究所 |
| 2000-07-03 |
2021-04-20 |
湖北大学 |
社会职务
科技部“工业酶产业技术创新战略联盟”专家委员会成员、副秘书长 中国微生物学会酶工程专业委员会委员 中国生物工程学会生物传感、生物芯片与纳米生物技术分会委员，2022-2027 中国生物发酵产业协会第二届理事会理事，酶制剂分会理事 中国食品科学技术学会酶制剂分会第六届理事会理事 微生物学报编委，2021-2026 微生物学通报编委，2024- Microbial cell factories, editor 湖北省暨武汉微生物学会酶工程专业委员会主任委员，2018-2023 湖北省暨武汉微生物学会真菌专业委员会副主任委员，2013-2023 湖北省暨武汉微生物学会常务理事，2018-2023
研究领域
（1）蛋白质工程的研究 发展各种蛋白质工程手段，致力于水解酶类的分子改造，具体如下：基于理性设计，实现了玉米赤霉烯酮降解酶、PG酶、内毒素降解酶、淀粉酶等酶的活性和稳定性的提高；基于半理性设计实现了木聚糖酶、果胶酶活性、稳定性的提高，和水解产物的改变；基于酵母表面展示结合分选型流式细胞仪进行高通量筛选，实现了HRV3C蛋白酶和SUMO蛋白酶切割位点的改变，实现了医用蛋白融合标签的无痕切除。 （2）精通大肠杆菌、枯草杆菌和毕赤酵母表达系统。 获得优秀的酶突变体以后，如何廉价的生产出来就需要构建一个高产的分泌表达工程菌株，因此申请人带领团队致力于大肠杆菌，枯草杆菌和毕赤酵母三个表达系统的优化，具体包括：大肠杆菌分泌表达和自裂解表达系统，能在目标蛋白大量表达之后，实现可控的菌体的自裂解释放目标蛋白；构建了枯草杆菌的基因编辑系统和双向调控系统，通过上调分子伴侣，下调蛋白酶，实现了枯草杆菌的同时双向调控，可以大幅提高异源蛋白的表达量；建立了通用的毕赤酵母高效表达策略，实现了多种异源蛋白的分泌表达和成果转化；构建了大肠杆菌，酵母的直接表面展示和间接表面展示系统，实现了基于细胞表面的级联催化和蛋白酶的高通量筛选体系。 （3）生物传感 真菌毒素，环境污染物的酶降解产物是否还有毒性常规通过细胞或者动物实验来进行，耗时耗钱。而通过微生物细胞来检测产物的毒性省时省力、微生物的培养成本也低廉，为降解产物的毒性检测提供了一个便利的检测体系。通过转录因子、启动子改造，宿主的筛选构建了水杨酸，苯甲酸及其衍生物的大肠杆菌检测体系，灵敏度比报道的提高了100-1000倍；通过核受体的改造，基于蛋白酶激活的级联放大系统，构建了雌激素等小分子化合物的酵母传感细胞，首次利用该传感系统筛选到了玉米赤霉烯酮真正的脱毒菌株。
本科生课程
| 课程名称 |
开课学年 |
课程总学时 |
选课人数 |
课程性质 |
| 微生物学 |
2023 |
56 |
80 |
专业必修 |
| 微生物学 |
2023 |
56 |
52 |
专业必修 |
| 微生物学 |
2023 |
56 |
6 |
专业选修 |
| 从分子观点了解生物学：结构生物学简介 |
2022 |
16 |
87 |
素质教育课程 |
| 微生物学 |
2022 |
56 |
30 |
专业必修 |
| 微生物学 |
2021 |
56 |
50 |
专业必修 |
| 细胞生物学与细胞工程 |
2021 |
48 |
44 |
专业必修 |
研究生课程
| 课程名称 |
开课学年 |
总学时 |
开课方式 |
| 微生物生物技术 |
2024 |
32 |
A公共基础课 |
| 微生物生物技术 |
2023 |
32 |
A公共基础课 |
| 微生物生物技术 |
2022 |
32 |
A公共基础课 |
| 微生物生物技术 |
2021 |
32 |
A公共基础课 |
纵向项目
- 1. 新污染物识别与毒性感知的高灵敏合成生物系统 ，国家重点研发计划，项目时间：2024-12-19 至 2029-11-30
- 2. 酵母底盘合成高分子量蛋白的关键技术与机制研究 ，省、市、自治区科技项目，项目时间：2024-10-01 至 2027-09-30
- 3. 玉米赤霉烯酮类真菌毒素分子识别机制研究及其酵母细胞传感器的构建 ，国家自然科学基金项目，项目时间：2024-01-01 至 2027-12-31
- 4. LPS降解酶的高效表达与生产 ，国家重点研发计划，项目时间：2022-11-07 至 2026-10-31
- 5. 枯草芽孢杆菌对真菌毒素玉米赤霉烯酮降解机制的研究 ，国家自然科学基金项目，项目时间：2020-01-01 至 2023-12-31
横向项目
- 1. 蛋白质谷氨酰胺酶产生菌解朊金黄杆菌的开发 ，企事业单位委托科技项目，项目时间：2023-07-03 至 2028-07-02
- 2. 质谱分析用系列蛋白酶的开发 ，企事业单位委托科技项目，项目时间：2022-11-20 至 2023-12-31
- 3. 纳米技术提高酶制剂催化效率和稳定性 ，自选课题，项目时间：2022-10-20 至 2023-10-19
- 4. 玉米赤霉烯酮降解酶定点突变改造设计 ，自选课题，项目时间：2022-05-09 至 2023-05-08
- 5. 金黄色葡萄球菌噬菌体裂解酶定点突变改造设计 ，其他研究项目，项目时间：2021-07-05 至 2022-07-04
论文信息
[+][-]代表性论文
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2030年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2029年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2028年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2027年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2026年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2025年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2024年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]
2023年
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
[+][-]2023年之前
-
1. DOI
Wang, Hui;Lu, Zhenghui;Lin, Xiaofan;Wang, Meixing;Jiang, Tianzhi;Zhao, Guoqiang;La Xiang;Xv, Jiazhan;Jiang, Sijing;Zhang, Guimin
The N-terminal hydrophobicity modulates a distal structural domain conformation of zearalenone lacton hydrolase and its application in protein engineering[期刊论文]，Enzyme and Microbial Technology，2023-04-01
-
2. DOI
Hu, Xinlin;Zhao, Xiang;Wang, Meixing;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Rationally tailoring the halophilicity of an amylolytic enzyme for application in dehydrating conditions[期刊论文]，Biochemical Engineering Journal，2022-12-31
-
3. DOI
Wang, Jiaheng;Zhang, Nuo;Huang, Yawen;Li, Shunyi;Zhang, Guimin
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: Complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-12-15
-
4. DOI
张桂敏
Simple and efficient enzymatic procedure for p-coumaric acid synthesis: complete bioconversion and biocatalyst recycling under alkaline condition[期刊论文]，Biochemical Engineering Journal，2022-10-25
-
5. DOI
Zhang, Faying;Zheng, Hui;Xian, Yufan;Song, Haoyue;Wang, Shengchen;Yun, Yueli;Yi, Li;Zhang, Guimin
Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS-PSSC System to Advance the Conserved Mechanism for Substrate Cleavage[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-10-01
-
6. DOI
Wang, Meixing;Hu, Huizhen;Zhang, Buyu;Zheng, Yang;Wu, Pan;Lu, Zhenghui;Zhang, Guimin
Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose[期刊论文]，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2022-07-01
-
7. DOI
Cui, Xin;Yuan, Xin;Li, Shunyi;Hu, Xinlin;Zhao, Jing;Zhang, Guimin
Simultaneously improving the specific activity and thermostability of α-amylase BLA by rational design[期刊论文]，Bioprocess and Biosystems Engineering，2022-01-01
专利
- 1. 一种比酶活提高的中性玉米赤霉烯酮降解酶突变体
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