Yingwei Zhang头像

Yingwei Zhang
  • Introduction
  • Research
  • Teaching
  • Funding
  • Publications
  • Awards
  • Honor Reward
  • Admission
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Fields ： DNA nanotechnology and biosensors
Associate professor 
Department ： College of Material Science and Engineering
Degree:
DBLPc:

Introduction

2013.01 to present

Associate Professor, School of Materials Science and Engineering, Beijing University of Chemical Technology

2016.12-2019.01
Visiting Scholar, Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, USA

2012.06-2012.12
Postdoctoral Researcher, School of Materials Science and Engineering, Nanyang Technological University, Singapore

2010.07-2012.05
Postdoctoral Researcher, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences

2005.09-2010.07
Ph.D., State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University

2001.09-2005.07
Bachelor’s degree in Materials Chemistry, School of Chemistry, Jilin University.


Education

Work Experience

Social Position

Social Activities

Research

Controlled assembly of DNA nanostructures based on DNA nanotechnology, such as DNA origami and DNA brick structures. This involves programming the guidance and regulation of static or dynamic assembly of functional micro-nano materials through DNA nanostructures, further exploring their applications in biosensing.


Controlled preparation and assembly of functional inorganic micro-nano materials, such as noble metal nanomaterials and their carbon composites, metal sulfides and composites, transition metal composite oxides, and quantum dot materials, while exploring their applications in biosensing, electrochemical detection, and related fields.

Teaching

Laboratory and Chemical Safety course

DNA Nanotechnology and Biosensors Course

Nucleic acid nanomaterials course

Postgraduates

Funding

National Natural Science Foundation of China (grants 52072024).

National Natural Science Foundation of China (grants 51672022).


Vertical Project

Horizontal Project

Publications

1.       Jingyan Mou, Haoping Zhang, Linghao Zhang, Beibei Zhang, Jiajia Liu, Shasha Zheng, Qiaoni Kou, Hong Wang, Xin Su,* Shaojun Guo, Yonggang Ke,* and Yingwei Zhang* Simulation-Guided Rational Design of DNA Walker-based Theranostic Platform, Small, 2024, 2400963.

 2.  Yingwei Zhang*, Aleks Reinhardt, Pengfei Wang, Jie Song, and Yonggang Ke*Programming the Nucleation of DNA Brick Self-Assembly with a Seeding Strand. Angew. Chem. Int. Ed. 2020, 59, 8594-8600.

3.     Yingwei Zhang*, Xianhui Chen, Guangjie Kang, Ruizi Peng, Victor Pan, Ranjani Sundaresan，Pengfei Wang* and Yonggang Ke*Programming DNA Tube Circumference by Tile Offset Connection. J. Am. Chem. Soc. 2019, 141, 19529−19532.

4.    Yingwei Zhang*, Victor Pan, Xue Li, Xueqin Yang, Haofei Li, Pengfei Wang* and Yonggang Ke*Dynamic DNA Structures. Small, 2019, 15, 1900228.

5.     Jinting Meng, Zihao Xu, Xinhao Li,  Baozheng Wang, Xiaowei Zhang, Zikang Xie, Chen Zhang, Hong Wang, Yingwei Zhang, Synergistic powering of DNA walker movement by endogenous dual enzymes for constructing dual-mode biosensors, Biosens. Bioelectron, 2024, 262, 116566.

6. Haoping Zhang, Min Pan, Xinyi Wang, Jingyu Tao, Zhaolong Tang, Hong Wang* and Yingwei Zhang, A Triple-Input AND-Logic System Employing an APE1-Propelled Bipedal DNA Walker for Highly Sensitive Detection of Dual miRNAs, ACS Sens. 2025, DOI:10.1021/acssensors.5c02731.

7. Baozheng Wang, Zixuan Ding, Wen Li, Hong Wang * and Yingwei Zhang * Dual-mode biosensor based on cascade CHA-HCR amplification and multilayer core-satellite nanostructures for highly sensitive microRNA detection, Sensors and Actuators: B. Chemical 2026, 448, 138939.

8. Beibei Zhang, Xinyi Wang, Min Pan, Xinhao Li, Hong Wang* and Yingwei Zhang, Sensitive detection of miRNA-141 using an endogenous dual-switch activated bipedal DNAzyme walker biosensor, Nanoscale, 2025,17, 20199-20206.

9. Zikang Xie, Zhaolong Tang, Xindie Zhuang, Xinhao Li, Baozheng Wang,Hong Wang* and Yingwei Zhang, A dual-switch fluorescence biosensor with an entropy-driven and DNA walker cascade amplification circuit for sensitive microRNA detection, Nanoscale, 2025,17, 8153-8160.

10.   A cascade signal-amplified fluorescent biosensor combining APE1 enzyme cleavage-assisted target cycling with rolling circle amplification, Analyst, 2024, 149, 82.

11.       Development of a regenerable dual-trigger tripedal DNA walker electrochemical biosensor for sensitive detection of microRNA-155, Anal. Chim. Acta，2024,1285, 342026.

12.    Electrochemical biosensor based on bipedal DNA walker for highly sensitive amplification detection of apurinic/apyrimidinic endonuclease 1, Sens. actuators. B Chem., 2023, 381, 133425。

13.    Dual-color graphene quantum dots and carbon nanoparticles biosensing platform combined with Exonuclease III-assisted signal amplification for simultaneous detection of multiple DNA targets，Anal. Chim. Acta，2021,1154, 338346

14.       Pengfei Wang,* Ji-Hyeok Huh, Haedong Park, Donglei Yang, Yingwei Zhang, Yunlong Zhang,

Jaewon Lee, Seungwoo Lee,* and Yonggang Ke* DNA Origami Guided Self-Assembly of Plasmonic Polymers with Robust Long-Range Plasmonic Resonance, Nano Lett. 2020, 20, 8926-8932.

15.    Dongfang Wang, Jie Song*, Pengfei Wang, Victor Pan, Yingwei Zhang, Daxiang Cui* and Yonggang Ke* Design and operation of reconfigurable two-dimensional DNA molecular arrays. Nature Protocols, 2018, 13, 2312-2329.

16.    Yingwei Zhang, Mengjiao Cheng, Yue Wang, and Feng Shi* Constructing a Multiplexed DNA Pattern by Combining Precise Magnetic Manipulation and DNA-Driven Assembly，Langmuir, 2018, 34, 1100-1108.

17.    Mengjiao Cheng, Yingwei Zhang,* Song Wang and Feng Shi* Macroscopic supramolecular assembly to fabricate multiplexed DNA patterns for potential application in DNA chips，Nanoscale, 2017, 9, 17220-17223.

18.    Song Wang, Yajun Zhang, Guangsheng Pang, Yingwei Zhang*, and Shaojun Guo* Tuning the Aggregation/Disaggregation Behavior of Graphene Quantum Dots by Structure-Switching Aptamer for High-Sensitivity Fluorescent Ochratoxin A Sensor, Anal. Chem., 2017, 89, 1704-1709.


Awards

Patent

Honor Reward

Admissions Information

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  • Email: zhangyw@mail.buct.edu.cn
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  • Office Location: Science and Technology Building1010
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