Yuyingjie头像

Yuyingjie

Professor Trainee

Research direction: Biomaterials, Tissue engineering, Metal elements, Cancer therapy

Education:

10 Access

  • Email: yuyingjie@mail.buct.edu.cn
  • Office : Organic Building 331
  • Introduction
  • Research
  • Teaching
  • Funding
  • Publications
  • Awards
  • Honor Reward
  • Admission

Introduction

Dr. Yingjie Yu is a Professor Trainee at the College of Materials Science and Engineering, Beijing University of Chemical Technology (BUCT). He earned his Ph.D. from Stony Brook University, State University of New York, and subsequently conducted postdoctoral research at the Massachusetts Institute of Technology (MIT) and Tufts University. 

His research primarily focuses on the development of biomedical polymeric materials. Specifically, he has systematically designed and developed a series of polymeric delivery systems for metal elements (including metal-based drugs and metal ions), providing critical strategies for their biomedical applications in cancer diagnosis and treatment, as well as tissue regeneration.

To date, Dr. Yu has published over 120 papers, with more than 50 as first or corresponding author in leading journals such as Nature Communications, Advanced Materials, Advanced Functional Materials, Coordination Chemistry Reviews, ACS Nano, and Bioactive Materials. He holds more than 10 invention patents. Additionally, Dr. Yu is the principal investigator of multiple funded projects, including the Beijing Distinguished Youth Fund, National Key R&D Program, the National Natural Science Foundation of China, and the Beijing Joint Fund.


Education

Work Experience

Social Position

Social Activities

Research

1. Biodegradable polymer for the delivery of metal elements 

2. Tissue engineering

3. Biosafety materials

4. Gene therapy and immunotherapy

Teaching

Postgraduates

Funding

Vertical Project

Horizontal Project

Publications

1. Sheng Lu, Yifan Li, Yingjie Yu*, Glutathione‐scavenging celastrol-Cu nanoparticles induce self-amplified cuproptosis for augmented cancer immunotherapy. Advanced Materials, 2024, 36, 2404971.

2. Hanchen Zhang, Nicolás Montesdeoca, Dongsheng Tang, Ganghao Liang, Minhui Cui, Chun Xu, Lisa-Marie Servos, Tiejun Bing, Zisis Papadopoulos, Meifang Shen, Haihua Xiao*, Yingjie Yu*, Johannes Karges*. Tumor-targeted glutathione oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma. Nature Communications, 2024, 15, 9405.

3. Liwen Zhang, Wenli Dai, Chenyuan Gao, Wei Wei, Ruiran Huang, Xin Zhang*, Yingjie Yu*, Xiaoping Yang, Qing Cai*. Multileveled hierarchical hydrogel with continuous biophysical and biochemical gradients for enhanced repair of full-thickness osteochondral defect. Advanced Materials, 2023,35, 202209565.

4. Dingge Liu, Xinyu Wang, Chenyuan Gao, Zhihua Zhang, Qi Wang, Yin Pei, Haijun Wang, Yujing Tang, Ke Li, Yingjie Yu*, Qing Cai*, Xin Zhang*. Biodegradable piezoelectric‐conductive integrated hydrogel scaffold for repair of osteochondral defects, Advanced Materials, 2024, 36, 2409400.

5. Yingjie Yu, Dongsheng Tang, Chaoyong Liu*, Qi Zhang, Lin Tang, Yunfeng Lu*, Haihua Xiao*. Biodegradable polymer with effective near-infrared-II absorption as photothermal agent for deep tumor therapy. Advanced Materials, 2021, 34, 2105976.

6. Bingzheng Yu, Yushu Wang, Tiejun Bing, Yujing Tang, Jia Huang, Haihua Xiao, Chaoyong Liu*, Yingjie Yu*. Platinum prodrug nanoparticles with COX‐2 inhibition amplify pyroptosis for enhanced chemotherapy and immune activation of pancreatic cancer, Advanced Materials, 2023, 36, 2310456.

7. Liangyu Wang, Yanyun Pang, Yujing Tang, Xinyu Wang, Daixing Zhang, Xu Zhang, Yingjie Yu*, Xiaoping Yang, Qing Cai*. A biomimetic piezoelectric scaffold with sustained Mg2+ release promotes neurogenic and angiogenic differentiation for enhanced bone regeneration, Bioactive Materials, 2022, 25, 399-414.

8. Yiqian Huang, Zhiyun Du, Ke Li, Wei Jing, Pengfei Wei, Bo Zhao*, Yingjie Yu*, Qing Cai*, Xiaoping Yang. ROS-scavenging electroactive polyphosphazene-based core–shell nanofibers for bone regeneration, Advanced Fiber Materials, 2022, 4, 894-907.

9. Meifang Shen, Yushu Wang, Tiejun Bing, Yujing Tang, Xueyi Liu, Yingjie Yu*. Alendronate triggered dual-cascade targeting prodrug nanoparticles for enhanced tumor penetration and STING activation of osteosarcoma, Advanced Functional Materials, 2023, 33, 2307013.

10. Xueyi Liu, Meifang Shen, Tiejun Bing, Xinyun Zhang, Yifan Li, Qing Cai, Xiaoping Yang, Yingjie Yu*. A bioactive injectable hydrogel regulates tumor metastasis and wound healing for melanoma via NIR‐light triggered hyperthermia, Advanced Science, 2024, 11, 2402208.


Awards

Patent

Honor Reward

Admissions Information