IntroductionDr. Lin is currently a professor of Materials Science and Engineering at Beijing University of Chemical Technology (BUCT). After receiving B.S. and PhD degree in Physical Chemistry from Peking University (under supervision of Prof. Jianbin Huang), he conducted post-doc research at The University of Oklahoma (with Prof. Chuanbin Mao) and Imperial College London (with Prof. Molly Stevens FRS FREng). In 2019, Dr. Lin joined BUCT to set up a research group working on soft functional materials. EducationWork ExperienceSocial PositionSocial ActivitiesResearchBiomaterials; Biomimetic chemistry; Artificial cells; Soft materials Teaching1)Laboratory and chemical safety 2) Organic Chemistry Laboratory 3)Advanced Biomaterials 4)Frontiers in Biomaterials PostgraduatesFundingVertical ProjectHorizontal ProjectPublications(1) J. Chen, K. Shi, R. Chen, Z. Zhai, P. Song, L.W. Chow, R. Chandrawati, E.T. Pashuck, F. Jiao, Y. Lin*, Supramolecular Hydrolase Mimics in Equilibrium and Kinetically Trapped States Angew. Chem. Int. Ed. 2024, 63, e2023178. (2) W. Mu, L. Jia, M. Zhou, J. Wu, Y. Lin*, S. Mann*, Y. Qiao*, Superstructural ordering in self-sorting coacervate-based protocell networks Nat. Chem.2024, 16, 158-167.封面文章,被Phys.org亮点报道 (3) K. Shi, X. Lv, J. Liu, Y. Lin*, J. Li*, Mechanically sensitive supramolecular materials Small Science2024, DIO: 10.1002/smsc.202300300. (4) Y. Yan, W. Mu, H. Li, C. Song, Y. Qiao*, Y. Lin*, Dynamical Behaviors of Oscillating Metallosurfactant Coacervate Microdroplets under Redox Stress Adv. Mater. 2023, 35, 2210700. (5) H. Li, Y. Yan, J. Chen, K. Shi, C. Song, Y. Ji, L. Jia, J. Li, Y. Qiao*, Y. Lin*, Artificial receptor-mediated phototransduction toward protocellular subcompartmentalization and signaling-encoded logic gates Sci. Adv. 2023, 9, eade5853. (6) X. Lv, J. Liu, P. Song, L. Zhao*, Y. Lin*, Instructing Liquid-Liquid Phase Separation Inside Membranous Protocells ChemSystemsChem2023, e202300040. (7) K. Shi, C. Song, Y. Wang, R. Chandrawati, Y. Lin*, Engineering receptor-mediated transmembrane signaling in artificial and living cells Commun. Mater.2023, 4, 65. (8) Y. Ji, Y. Lin, Y. Qiao*, Plant Cell-Inspired Membranization of Coacervate Protocells with a Structured Polysaccharide Layer J. Am. Chem Soc. 2023, 145, 23, 12576–12585. (9) M. Wei, Y. Lin*, Y. Qiao*, Engineered colloidosomes as biomimetic cellular models Giant 2023, 13, 100143. (10)M. Zhu, J. Chen, Y. Lin*, Exploring chemical space and structural diversity of supramolecular peptide materials Supramolecular Materials 2023, 2, 100030. (11)X. Xiao, J. Huang, Y. Lin*, Y. Qiao*, Small Amphiphile-Based Coacervation Chem Asian J 2022 17, e2022009. (12)A. Najer*, et al. “Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo” ACS Cent. Sci.2022, 8, 9, 1238–1257. (13)F. Li, Y. Lin*, Y. Qiao*, Regulating FUS Liquid-Liquid Phase Separation via Specific Metal Recognition Chinese J. Polym. Sci. 2022, 40, 1043–1049. (14)W. Mu, Z. Ji, M. Zhou, J. Wu, Y. Lin*, Y. Qiao*, Membrane-confined liquid-liquid phase separation toward artificial organelles Sci Adv 2021, 7, eabf9000. 被Nature、Phys.org等亮点报道 (15)Y. Xianyu*, Y. Lin, Q. Chen, A. Belessiotis‐Richards, M. M. Stevens, M. R. Thomas, Iodide‐Mediated Rapid and Sensitive Surface Etching of Gold Nanostars for Biosensing Angew. Chem. Int. Ed. 2021, 60, 9891-9896. (16)Y. Lin, M. Penna, C. D. Spicer, S. G. Higgins, A. Gelmi, N. Kim, S.-T. Wang, J. P. Wojciechowski, E. T. Pashuck, I. Yarovsky*, M. M. Stevens*, High-Throughput Peptide Derivatization toward Supramolecular Diversification in Microtiter Plates ACS Nano 2021, 15, 3, 4034–4044. (17)L. Ouyang, J. Armstrong, Y. Lin, J. Wojciechowski, C. Lee-Reeves, D. Hachim, K. Zhou, J.A. Burdick, M. Stevens*, Expanding and optimizing 3D bioprinting capabilities using complementary network bioinks Sci. Adv. 2020, 6, eabc5529. (18)N. Amdursky*, Y. Lin, Tracking subtle membrane disruptions with a tethered photoacid ChemPhotoChem 2020, DOI: 10.1002/cptc.202000024R1. (19)S.-T. Wang, M. A. Gray, S. Xuan, Y. Lin, J. Byrnes, A. I. Nguyen, N. Todorova, M. M. Stevens, C. R. Bertozzi, R. N. Zuckermann, and O. Gang*, “DNA origami protection and molecular interfacing through engineered sequence-defined peptoids” Proc. Natl. Acad. Sci. U.S.A 2020, 117, 6339–6348. (20)Y. Lin,§ M. Mazo,§ S. S. Skaalure, M. R. Thomas, S. R. Schultz, M. M. Stevens* “Activatable cell-biomaterial interfacing with photo-caged peptides” Chem. Sci. 2019, 10, 1158–1167. (21)Y. Lin, M. Penna, M. R. Thomas, V. Leonardo, Y. Wang, E. T. Pashuck, I. Yarovsky,* M. M. Stevens*, “Residue-Specific Solvation Directed Thermodynamic and Kinetic Control over Peptide Self-Assembly with 1D/2D Structure Selection” ACS Nano 2019, 13, 1900–1909. (22)N. Amdursky*, Y. Lin, N. Aho, G. Groenhof, “Exploring fast proton transfer events associated with lateral proton diffusion on the surface of membranes” Proc. Natl. Acad. Sci. U.S.A 2019, 116, 2443–2451. (23)C.-C. Li, L. O, I. J. Pence, A. C. Moore, Y. Lin, C. W. Winter, J. P. K. Armstrong*, M. M. Stevens*, “Buoyancy-Driven Gradients for Biomaterial Fabrication and Tissue Engineering” Adv. Mater 2019, 31, 1900291. (24)L. Ouyang, J. P. K. Armstrong, Q. Chen, Y. Lin, M. M. Stevens* Void-Free 3D Bioprinting for In Situ Endothelialization and Microfluidic Perfusion Adv. Funct. Mater. 2019, 1908349. (25)C. N. Loynachan, A. P. Soleimany, J. S. Dudani, Y. Lin, A. Najer, A. Bekdemir, Q. Chen, S. N. Bhatia*, M. M. Stevens*, “Renal clearable catalytic gold nanoclusters for in vivo disease monitoring” Nat. Nano. 2019, 14, 883–890. (26)S.-T. Wang, Y. Lin, M. H. Nielsen., C. Song., M. R. Thomas, C. D. Spicer, R. Kröger, P. Ercius, S. Aloni, and M. M. Stevens*, “Shape-Controlled Synthesis and In Situ Characterisation of Anisotropic Au Nanomaterials using Liquid Cell Transmission Electron Microscopy” Nanoscale2019, 11, 16801-16809. (27)Y. Wang, E. Kim, Y. Lin, N. Kim, W. Kit-Anan, S. Gopal, S. Agarwal, P. D. Howes, M. M. Stevens*, Rolling circle transcription-amplified hierarchically structured organic-inorganic hybrid RNA flowers for enzyme immobilization ACS Appl. Mater. Interfaces 2019, 11, 2622932-22940. (28)X. J. Wang, Y. X. Liu, Y. Lin, Y. C. Han, J. B. Huang, J. Zhou, and Y. Yan*, “Trojan Antibiotics: New Weapons for Fighting Against Drug Resistance” ACS Appl. Bio Mater. 2019, 2, 447–453. (29)Y. Lin,§ P. Charchar,§ A. J. Christofferson, M. R. Thomas, N. Todorova, M. M. Mazo, Q. Chen, J. Doutch, R. Richardson, I. Yarovsky*, M. M. Stevens*, “Surface Dynamics and Ligand-Core Interactions of Quantum Sized Photoluminescent Gold Nanoclusters” J. Am. Chem. Soc. 2018, 140, 18217−18226. (30)Y. Wang, P. D. Howes, E. J. Kim, C. D. Spicer , M. R. Thomas , Y. Lin, S. W. Crowder, I. J. Pence, M. M. Stevens*, “Duplex-Specific Nuclease-Amplified Detection of MicroRNA Using Compact Quantum Dot–DNA Conjugates” ACS Appl. Mater. Interfaces 2018, 10, 28290–28300. (31)Y. Lin, M. R. Thomas, A. Gelmi, V. Leonardo, E. T. Pashuck, S. A. Maynard, Y. Wang, M. M. Stevens* “Self-assembled 2D Free-Standing Janus Nanosheets with Single-Layer Thickness” J. Am. Chem. Soc. 2017, 139, 13592–13595. (32)Y. Lin, E. T. Pashuck, M. R. Thomas, N. Amdursky, S.-T. Wang, L. W. Chow, M. M. Stevens*, “Plasmonic Chirality Imprinting on Nucleobase-Displayed Supramolecular Nanohelices via Metal-Nucleobase Recognition”, Angew Chem Int Ed. 2017, 56, 2361-2365. (Hot Paper, highlighted by Chemistry Views) (33)S.-T. Wang, Y. Lin, R. Spencer, M. Thomas, A. Nguyen, N. Amdursky, E. Pashuck, S. S. Skaalure, C. Song, P. Parmar, R. Morgan, P. Ercius, S. Aloni, R. Zuckermann, M. Stevens, “Sequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β-Sheet Fibrils” ACS Nano 2017, 11, 8579–8589. (34)J. H. Soh, Y. Lin, M. R. Thomas, N. Todorova, C. Kallepitis, I. Yarovsky, J. Y. Ying, M. M. Stevens* “Distinct Bimodal Roles of Aromatic Molecules in Controlling Gold Nanorod Growth and Their Application in Biosensing” Adv. Funct. Mater. 2017, 27, 1700523. (35)S.-T. Wang, Y. Lin, N. Todorova, Y. Q. Xu, M. Mazo, S. Rana, V. Leonardo, N. Amdursky, C. D. Spicer, B. D. Alexander, A. A. Edwards, S. J. Matthews, I. Yarovsky, M. M. Stevens*, “Facet Dependent Islet Amyloid Polypeptide Interactions with Gold Nanoparticles: Implications for Fibril Formation and Peptide-Induced Lipid Membrane Disruption”, Chem. Mater. 2017, 29, 1550-1560. (36)J. Liu, R. Chapman, Y. Lin, A. Bentham, M. Tyreman, N. Philips, S. A. Khan, M. M. Stevens*, Phospholipase A2 as a point of care alternative to serum amylase and pancreatic lipase Nanoscale 2016, 8, 11834-11839. (37)N. J. Liu, R. Chapman, Y. Lin, J. Mmesi, A. Bentham, M. Tyreman, S. Abraham, M. M. Stevens*, Point of care testing of phospholipase A2 group IIA for serological diagnosis of rheumatoid arthritis Nanoscale 2016, 8, 4482-4485. (38)Y. Lin, R. Chapman, M. M. Stevens*, Integrative Self-Assembly of Graphene Quantum Dots and Biopolymers into a Versatile Biosensing ToolkitAdv. Funct. Mater. 2015, 25, 3183–3192. (39)R. Chapman§, Y. Lin§, M. Burnapp, A. Bentham, D. Hillier, A. Zabron, S. Khan, M. Tyreman, M. M. Stevens*, Multivalent Nanoparticle Networks Enable Point-of-Care Detection of Human Phospholipase-A2 in Serum ACS Nano 2015, 9, 2565–2573. (§Equal Contribution) (40)S.-T. Wang, Y. Lin, C.-C. Hsu, N. Amdursky, C. D. Spicer, M. M. Stevens*, Probing Amylin Fibrillation at an Early Stage via a Tetracysteine-Recognising Fluorophore Talanta 2017, 173, 44-50. (41)S.-T. Wang, Y. Lin, C. D. Spicer, M. M. Stevens*, Bio-Inspired Reactions Enable a Simple and Sensitive Assay for Colorimetric Detection of MethylglyoxalChem. Comm. 2015, 51, 11026-11029. (42)J. H. Soh, Y. Lin, J. Y. Ying, M. M. Stevens*, Colorimetric Detection of Small Molecules in Complex Matrices via Target-Mediated Growth of Aptamer-Functionalized Gold Nanoparticles Anal. Chem. 2015, 87, 7644-7652. (43)Y. Lin, R. Chapman, M. M. Stevens*, Label-Free Multimodal Protease Detection Based on Protein/Perylene Dye Coassembly and Enzyme-Triggered Disassembly Anal. Chem., 2014, 86, 6410–6417. (44)H. Xie,Y. Lin, M. Mazo, C. Chiappini, A. Sánchez-Iglesias, L. M. Liz-Marzán, M. M. Stevens*, Identification of Intracellular Gold Nanoparticles Using Surface-enhanced Raman Scattering, Nanoscale 2014, 6, 12403-12407. (45)K. Ma, D.-D. Wang, Y. Lin, J. L. Wang, V. Petrenko, C. B. Mao*, Synergetic Targeted Delivery of Sleeping-Beauty Transposon System to Mesenchymal Stem Cells Using LPD Nanoparticles Modified with a Phage-Displayed Targeting Peptide Adv. Funct. Mat. 2013, 23, 1172–1181. (46)Y. Qiao, Y. Lin, S. Liu, S. F. Zhang, H. F. Chen, Y. J. Wang, Y. Yan, X. F. Guo, J. B. Huang*, Metal-driven hierarchical self-assembled zigzag nanoarchitectures with electrical conductivity Chem. Commun.2013, 49, 704-706. (47)Y. Lin, Y. Qiao, Y. J. Wang, Y. Yan, J. B. Huang*, Self-assembled Laminated Nanoribbons Directed Synthesis of Noble Metallic Nanoparticles-Decorated Silica Nanotubes and Their Catalytic Applications J. Mater. Chem.2012, 22, 18314-18320. (48)Y. Lin, Y. Qiao, X. H. Cheng, Y. Yan, J. B. Huang*, Z. B. Li, Hydrotropic Salt Promotes Anionic Surfactant Self-Assembly into Vesicles and Ultralong Fibers J. Colloid Interface Sci. 2012, 369, 238-244. (49)Y.Lin, Y. Qiao, P. F. Tang, Z. B. Li, J. B. Huang*, “Controllable Self-Assembled Laminated Nanoribbons from Dipeptide-Amphiphile Bearing Azobenzene Moiety” Soft Matter 2011,7, 2762–2769. (50)Y. Lin, C. B. Mao*, “Bio-inspired Supramolecular Self-assembly toward Soft Materials” Front. Mater. Sci. 2011, 5, 247–265. (51)Y. Lin, Y. D. Zhang, Y. Qiao, J. B. Huang*, “Light and Host-Guest Inclusion Mediated Salmon Sperm DNA/Surfactant Interactions” J. Colloid Interface Sci.2011, 362, 430-438. (52)Y. Qiao,Y. Lin, J. B. Huang*, “Lanthanide-Containing Photoluminescent Materials: from Hybrid Hydrogel to Inorganic Nanotubes” Chem. Eur. J. 2011, 17, 5180–5187. (53)Y. Yan, Y. Lin, Y. Qiao, J. B. Huang*, “'Construction and Application of Tunable One-Dimensional Soft Supramolecular Assemblies” Soft Matter 2011, 7, 6385–6398. (54)Y. Qiao, Y. Lin, Y. J. Wang, Y. Yan, and J. B. Huang*, “Metal-Driven Viscoelastic Wormlike Micelle in Anionic/Zwitterionic Surfactant System and Template-Directed Synthesis of Dendritic Silver Nanostructures”Langmuir 2011, 27, 1718–1723. (55)Y. Qiao, H. F. Chen, Y. Lin, J. B. Huang*, “Photoluminescent Lanthanide-Doped Silica Nanotubes: Sol-Gel Transcription from Functional Template” J. Phys. Chem. C 2011, 115, 7323–7330. (56) Y. Qiao, H. F. Chen, Y. Lin, J. B. Huang*, “Controllable Synthesis of Water-Soluble Gold Nanoparticles and Their Applications in Electrocatalysis and Surface-Enhanced Raman Scattering” Langmuir 2011, 27, 11090–11097. (57)Y. Qiao, Y. J. Wang, Z. Y. Yang, Y. Lin, J. B. Huang*, “Self-templating of Metal-Driven Supramolecular Self-assembly: A General Approach toward 1D Inorganic Nanotubes”Chem. Mater. 2011, 23, 1182–1187. (58)Y. Lin, Y. Qiao, C. Gao, P. F. Tang, Z. B. Li, Y. Yan, J. B. Huang*, “Tunable One-Dimensional Helical Nanostructures: from Supramolecular Self-Assemblies to Inorganic Nanomaterials” Chem. Mater. 2010, 22, 6711-6717. (59)Y. Lin, A. D. Wang, Y. Qiao, X. Li, M. Drechsler, Y. Yan, J. B. Huang*, J. P. Ye, “Rationally Designed Hierarchical Double Helix via Multiple Non-Covalent Interactions: Fabrication and Modification”Soft Matter 2010, 6, 2031-2036. (60)Y. Lin, X. H. Cheng, Y. Qiao, A. D. Wang, C. L. Yu, Y. Yan, J. B. Huang*, “Creation of Photo-Modulated Multi-State and Multi-Scale Molecular Assemblies via Binary-State Molecular Switch” Soft Matter 2010, 6, 902-908. (61)Y. Qiao, Y. Lin, Z. Y. Yang, H. F. Chen, S. F. Zhang, Y. Yan, and J. B. Huang*, “Unique Temperature-Dependent Supramolecular Self-Assembly: From Hierarchical 1D Nanostructures to Super Hydrogel” J. Phys. Chem. B 2010, 114, 11725–11730. (62)D. F. Yu, X. Huang, M. L. Deng, Y. Lin, L. X. Jiang, J. B. Huang*, and Y. L. Wang*, “Effects of Inorganic and Organic Salts on Aggregation Behavior of Cationic Gemini Surfactants” J. Phys. Chem. B. 2010, 114, 14955-14964. (63)Y. Lin, Y. Qiao, Y. Yan, J. B. Huang*, “Thermo-Responsive Viscoelastic Wormlike Micelle to Elastic Hydrogel Transition in Dual-Component Systems” Soft Matter 2009, 5, 3047-3053. (64)Y. Qiao, Y. Lin, Y. J. Wang, J. Liu, Z. Y. Yang, Y. Yan, J. B. Huang*, “Metal-Driven Hierarchical Self-Assembled One-Dimensional Nanohelices” Nano Lett 2009, 9, 4500-4504. (65)Y. Lin, X. Han, H. L. Fu, C. L. Yu, J. B. Huang*, “A Facile Route to Design pH-Responsive Viscoelastic Wormlike Micelle: Smart Use of Hydrotrope” J. Colloid Interface Sci. 2009, 330, 449-455. (66)H. Q. Yin, Y. Lin, J. B. Huang*, “Microstructures and Rheological Dynamics of Viscoelastic Solutions in a Catanionic Surfactant System” J. Colloid Interface Sci. 2009, 338, 177-183. (67)Y. Lin, X. Han, X. H. Cheng, J. B. Huang*, D. L. Liang, C. L. Yu, “pH-Regulated Molecular Self-Assemblies in a Cationic-Anionic Surfactant System: From ‘1-2’ Surfactant Pair to ‘1-1’ Surfactant Pair” Langmuir 2008, 24, 13918-10924. (68)H. Q. Yin, Y. Lin, J. B. Huang*, J. P. Ye, Temperature-Induced Vesicle Aggregation in Catanionic Surfactant Systems: Effects of the Headgroup and Counterion Langmuir 2007, 23, 4225-4230. (69)H. Q. Yin, J. B. Huang*, Y. Lin, Y. Y. Zhang, S. C. Qiu, J. P. Ye, “The Research on the Temperature-induced Micelle to Vesicle Transition in Cationic-anionic Surfactant Systems” J. Phys. Chem. B 2005, 109, 4104-4110. AwardsPatentHonor RewardAdmissions Information |