Helei头像

Helei

Associate professor

Research direction:

Education:

10 Access

  • Email: helei@mail.buct.edu.cn
  • Office :
  • Introduction
  • Research
  • Teaching
  • Funding
  • Publications
  • Awards
  • Honor Reward
  • Admission

Introduction

Biography

Academic Qualifications:

  • B.S., Pharmaceutical Science, Tianjin University (2007.9-2011.6)

  • B.S., Finance, Nankai University (2009.2-2011.6)

  • M.S., Chemistry, Renmin University of China (2011.9-2014.6)

  • Ph.D., Chemistry, Nanyang Technological University (2014.8-2019.1)

Working Experience:

  • Postdoctoral Research Fellow, Nanyang Technological University (2019.1-2019.9)

  • Associate Professor, Beijing University of Chemical Technology (2019.9-current)


Education

Work Experience

Social Position

Social Activities

Research

Research Interests

My research interests lie in highly interdisciplinary area at the interface of bioinorganic chemistry, chemical biology, nanomedicine and electrochemistry. Specifically, my research focuses on: a) the development of anticancer drugs for targeted therapy; b) the design of multi-targeted agents against neurodegenerative diseases; c) the construction of polyoxometalate-based materials for energy conversion and storage.


Teaching

Postgraduates

Funding

Projects &Funding

  • National Natural Science Foundation of China for Young Scholars (Grant No. 22007004), 2021.1-2023.12

  • Fundamental Research Funds for the Central Universities (Grant No. buctrc202010), 2020.1-2023.12


Vertical Project

Horizontal Project

Publications

  1. Bole Li, Xiaotong Xu, Yanfei Lv, Lei He* and Yu-Fei Song*, Polyoxometalates as potential artificial enzymes toward biological applications. Small, 2023, DOI: 10.1002/smll.202305539.

  2. Bole Li#, Chang Xu#, Yanfei Lv, Guihao Liu, Xiaoliang Sun, Zeqian Sun, Xiaotong Xu, Wei Chen, Lei He* and Yu-Fei Song*, Vanadium-Substituted Polyoxometalates Regulate Prion Protein Fragment 106-126 Misfolding by an Oxidation Strategy. ACS Appl. Mater. Interfaces, 2023, 15, 34497-34504.

  3. Lin Guo, Lei He*, Qinghe Zhuang, Bole Li, Cuifeng Wang, Yanfei Lv, Jinfeng Chu* and Yu-Fei Song*, Recent Advances in Confining Polyoxometalates and the Applications. Small, 2023, 19, 2207315.

  4. Dongwei Cao, Quan Sha, Jiaxin Wang, Jiaxin Li, Jing Ren, Tianyang Shen, Sha Bai, Lei He* and Yu-Fei Song*, Advanced anode materials for sodium-ion batteries: confining polyoxometalates in flexible metal–organic frameworks by the “breathing effect”, ACS Appl. Mater. Interfaces,2022, 14, 22186-22196.

  5. Jiaxin Wang, Yubing Liu, Quan Sha, Dongwei Cao, Hanbin Hu, Tianyang Shen, Lei He* and Yu-Fei Song*, Electronic structure reconfiguration of self-supported polyoxometalate-based lithium-ion battery anodes for efficient lithium storage, ACS Appl. Mater. Interfaces,2022,14, 1169-1176.

  6. Cuifeng Wang, Zhaohui Wu, Guihao Liu, Sha Bai, Lin Guo, Lei He* and Yu-Fei Song*, Highly efficient electrochemical CO2 reduction over crystalline-amorphous In2O3-CeOx heterostructures,Inorg. Chem. Front., 2022, 9, 5926-5931.

  7. Quan Sha, Dongwei Cao*, Jiaxin Wang, Hanbin Hu, Jiaxin Li, Wei Chen, Lei He*, Graham N. Newton* and Yu-Fei Song*, Insight into the structural variation and sodium storage behavior of polyoxometalates encapsulated within single-walled carbon nanotubes, Chem. Eur. J., 2022, e202201899.

  8. Xinning Song#, Shunhan Jia#, Liang Xu, Jiaqi Feng, Lei He*, Xiaofu Sun* and Buxing Han*, Towards sustainable CO2 electrochemical transformation via coupling design strategy, Mater. Today. Sustain., 2022, 19, 100179.

  9. Wenyu Tian, Lin Guo, Hanbin Hu, Jinfeng Chu, Lei He* and Yu-Fei Song*, Frontiers and applications of polyoxometalates-based porous ionic crystals, Chinese Science Bulletin,2022, 67, 655-669.

  10. Hanbin Hu, Xueying Jia, Jiaxin Wang, Wei Chen*, Lei He* and Yu-Fei Song*, Confinement of PMo12 in hollow SiO2-PMo12@rGO nanospheres for high-performance lithium storage, Inorg. Chem. Front., 2021, 8, 352-360.

  11. Jiaxin Wang, Xiaoliang Sun, Hanbin Hu, Tianyang Shen, Guihao Liu, Zewei Li, Dongwei Cao, Lei He* and Yu-Fei Song*, Electrodeposition of defect-rich ternary NiCoFe layered double hydroxides: fine modulation of Co3+ for highly efficient oxygen evolution reaction, Chem. Eur. J., 2021, e202103601.

  12. Hanbin Hu, Yixin Yang, Xiao Jiang, Jiaxin Wang, Lei He*, Wei Chen* and Yu-Fei Song*, Double-shelled hollow SiO2@N-C nanofiber boosts the lithium storage performance of PMo12, Chem. Eur. J., 2021, 27, 13367-13375.

  13. Jiaxin Li, Bei Li, Jikang Wang, Lei He* and Yufei Zhao*, Recent advances in layered double hydroxides andtheir derivatives for biomedical applications, Acta Chim. Sinica, 2021, 79, 238-256.

  14. Bushra Iqbal, Xueying Jia, Hanbin Hu, Lei He*, Wei Chen and Yu-Fei Song*, Fabrication of redox-active polyoxometalatebased ionic crystals onto single-walled carbon nanotubes as high-performance anode materials for lithium-ion batteries, Inorg. Chem. Front., 2020, 7, 1420-1427.

  15. Poe Ei Phyu Win, JiaXin Wang, XueYing Jia, Bo Qi, Wei Chen, Lei He* and Yu-Fei Song*, Synergistic effects of polyoxometalate with MoS2 sheets on multiwalled carbon nanotubes backbone for high-performance supercapacitor, J. Alloys Compd.,2020, 844, 156194.

  16. Lei He, Zhenyu Meng, Qianqian Guo, Xiangyang Wu, Marie-Paule Teulade-Fichou, Edwin Kok Lee Yeow and Fangwei Shao*, Fluorogenic Pt complexes distinguish the quantity and folding behavior of RNA G-quadruplexes between live cancerous and healthy cells, Chem. Commun., 2020, 56, 14459-14462.

  17. Lei He, Xiaofu Sun, Hua Zhang*, and Fangwei Shao*, G-quadruplex nanowires to direct the efficiency and selectivity of electrocatalytic CO₂ reduction, Angew. Chem. Int. Ed., 2018, 57, 12453.

  18. Lei He#, Zhenyu Meng#, Dechen Xu and Fangwei Shao*, Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex, Sci. Rep., 2018, 8, 767.

  19. Lei He#, Zhenyu Meng#, Yiqun Xie#, Xiang Chen, Tianhu Li and Fangwei Shao*, Aza-bridged bisphenanthrolinyl Pt(II) complexes: Efficient stabilization and topological selectivity on telomeric G-quadruplexes, J. Inorg. Biochem., 2017, 166, 135-140.

  20. Lei He#, Xiang Chen#, Zhenyu Meng, Jintao Wang, Keyin Tian, Tianhu Li and Fangwei Shao*, Octahedral ruthenium complexes selectively stabilize G-quadruplexes, Chem. Commun., 2016, 52, 8095-8098.

  21. Lei He#, Xuesong Wang#, Dengsen Zhu, Cong Zhao and Weihong Du*, Methionine oxidation of amyloid peptides by peroxovanadium complexes: inhibition of fibril formation through a distinct mechanism, Metallomics, 2015, 7, 1562-1572.

  22. Lei He, Dengsen Zhu, Cong Zhao, Xian Jia, Xuesong Wang, Weihong Du*, Effects of gold complexes on the assembly behavior of human islet amyloid polypeptide, J. Inorg. Biochem., 2015, 152, 114-122.

  23. Lei He, Xuesong Wang, Cong Zhao, Dengsen Zhu and Weihong Du*, Inhibition of human amylin fibril formation by insulin-mimic vanadium complexes, Metallomics, 2014, 6, 1087-1096.

  24. Lei He, Xuesong Wang, Cong Zhao, Hongfei Wang and Weihong Du*, Ruthenium complexes as novel inhibitors of human islet amyloid polypeptide fibril formation, Metallomics, 2013, 5, 1599-1603.


Awards

Patent

Honor Reward

Admissions Information