Wang Shaojie

Associate professor

Department： School of of Life Sciences and Technology

Fields: Green Biorefinery & Synthetic Biology

Email: wangshaojie@buct.edu.cn

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10 Visits

Introduction

Associate Professor, Master's Supervisor, selected as a young talent in the Beijing Youth Talent Support Program. In 2013, he obtained a master's degree in engineering from Beijing University of Chemical Technology, and in 2018, he obtained a doctoral degree in engineering from the same university. He was a visiting scholar at Washington University in St. Louis, USA from 2017 to 2018, and worked as a postdoctoral researcher at Shanghai Jiao Tong University from 2019 to 2021. He was awarded the Morning Star Postdoctoral Incentive Plan at Shanghai Jiao Tong University in 2019 and was an outstanding undergraduate thesis supervisor in Beijing in 2022.

He has published over 30 papers as the first or corresponding author in journals such as Adv Sci, Biotechnol. Adv, Bioresource Technol, Sci Total Environ, including one hot paper and cover paper. He has hosted 5 research projects, including 3 national-level projects.

Education Work Experience

Social Position

Social Activities

Research

RESEARCH INTERESTS

(1) Construction of genome-scale metabolic network models

Construct and optimize genome-scale metabolic network models, integrate composite constraints to improve model simulation accuracy, analyze metabolic regulation targets and pathway modification strategies, and rationally guide the design and construction of cell factories.

(2) Construction of high-performance microbial single/multi-cell factories

Based on metabolic network model construction and simulation design, combined with metabolic engineering and synthetic biology technology, develop high-performance microbial single/multi-cell factories to achieve efficient synthesis of non-natural amino acids, monomers of biobased materials, and other products.

Teaching

Postgraduates

Funding

Vertical Project

Horizontal Project

Publications

SELECTED PUBLICATIONS

[1] Yu Liu, Boyuan Xue, Hao Liu, Shaojie Wang*, Haijia Su*. Rational construction of synthetic consortia: Key considerations and model-based methods for guiding the development of a novel biosynthesis platform. Biotechnology Advances, 2024, 72, 108348.

[2] Boyuan Xue, Yu Liu, Chen Yang, Hao Liu, Qianqian Yuan, Shaojie Wang*, Haijia Su*. Co‐Cultivated Enzyme Constraint Metabolic Network Model for Rational Guidance in Constructing Synthetic Consortia to Achieve Optimal Pathway Allocation Prediction. Advanced Science, 2023: 2306662.

[3] Wei Xiong#, Shaojie Wang#, Qiuhua Zhang, Yiran Hou, Yu Jin, Biqiang Chen, Haijia Su*. Synergistic analysis of performance, microbial community, and metabolism in aerobic granular sludge under polyacrylonitrile microplastics stress, Bioresource Technology. 2023, 385, 129394.

[4] Jiangbo Li, Kai Wang, Shaojie Wang*, Haijia Su*. Spatially-ordered layer-by-layer biofilms of a two-species microbial consortium promote hydrogen production, Renewable Energy, 2023, 215, 118905.

[5] Yu Jin, Wei Xiong, Dan Liu, Zhiqing Wu, Gang Xiao, Shaojie Wang*, Haijia Su*. Responses of straw foam-based aerobic granular sludge to atrazine: Insights from metagenomics and microbial community variations, Chemosphere, 2023, 331, 138828.

[6] Yaoqiang Wang, Yilin Zhao, Shaojie Wang*, Gang Xiao*, Yu Jin, Zishuai Wang, and Haijia Su*. Visible-Light-Driven Enhanced Biohydrogen Production by Photo- Biohybrid System Based on Photoelectron Transfer between Intracellular Photosensitizer Gold Nanoparticles and Clostridium butyricum, ACS Sustainable Chemistry & Engineering, 2023,11, 300-311.

[7] Peiqi Cui #, Shaojie Wang #, Haijia Su*. Enhanced biohydrogen production of anaerobic fermentation by the Fe3O4 modified mycelial pellets-based anaerobic granular sludge, Bioresource Technology, 2022, 366, 128144.

[8] Peiqi Cui, Jiye Ge, Yingyun Chen, Yilin Zhao, Shaojie Wang*, Haijia Su*. The Fe₃O₄ nanoparticles-modified mycelium pellet-based anaerobic granular sludge enhanced anaerobic digestion of food waste with high salinity and organic load, Renewable Energy, 2022, 185, 376-385.

[9] Yu Jin, Wei Xiong, Nan Zhou, Gang Xiao, Shaojie Wang*, Haijia Su*. Role of initial bacterial community in the aerobic sludge granulation and performance, Journal of Environmental Management, 2022, 309, 114706.

[10] Yingyun Chen, Jiye Ge, Shaojie Wang*, Haijia Su*. Insight into formation and biological characteristics of Aspergillus tubingensis-based aerobic granular sludge (AT-AGS) in wastewater treatment. Science of The Total Environment, 2020, 739: 140128.

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