Shenxiaolin头像

Shenxiaolin

Professor

Research direction:

100029

Education:

  • Department: College of life science and biotechnology
  • ORCID:
  • DBLP:

10 Access

  • Email: shenxl@buct.edu.cn
  • Office :
  • Introduction
  • Research
  • Teaching
  • Funding
  • Publications
  • Awards
  • Honor Reward
  • Admission

Introduction

Shen Xiaolin, professor. She has been selected as one of the national young talents, She has been selected as one of the national young talents, She has been selected as one of the national young talents, She has been selected as one of the national young talents, She has been selected as one of the national young talents and the Young Talents Program of Beijing University of Chemical Technology. Her primary research interests lie in the field of Synthetic Biology and Metabolic Engineering within microorganisms. She received a Ph.D. degree from Beijing University of Chemical Technology in 2013, and further expanded her expertise during her postdoctoral tenure from 2015 to 2018 at the University of Georgia. She has published more than 30 articles in top journals as the first author or corresponding author, and has applied 13 patents (3 has been issued). Her work has been supported by funding from the National Natural Science Foundation of China, National Key Research and Development program of China, Key Research and Development plan of Guangdong Province. She has given oral presentations on international conferences such as AICHE Annual Meeting for many times. She is also a member of the Youth Work Committee of the China Association of Bioengineering.


Education

Work Experience

Social Position

Social Activities

Research

Main Research Areas:

The main research interests of the laboratory are metabolic engineering and synthetic biology.

1. Natural Product Biosynthesis；

2. Biosynthesis of non-natural drugs


Teaching

Postgraduates

Funding

Vertical Project

Horizontal Project

Publications

Recent publications:

1.      Jingyan Wang, Qiangjing Zhao, Xin Chen, Yichen Lu, Xinxiao Sun, Qipeng Yuan, Jia Wang*, Xiaolin Shen*. Engineering a novel pathway for efficient biosynthesis of salicin in Escherichia coli. Metabolic Engineering. 2024, 86, 172-180.

2.      Liangpo Li, Linwei Yu, Xinxiao Sun, Qipeng Yuan, Xiaolin Shen*, Jia Wang*. Synthetic auxotrophs accelerate cell factory development through growth-coupled models. Frontiers of Chemical Science and Engineering. 2024, 18, 1-15.

3.      Jun Wu, Jia Wang, Yicheng Zeng, Xinxiao Sun, Qipeng Yuan, Ling Liu*, Xiaolin Shen*. Biodegradation: the best solution to the world problem of discarded polymers. Bioresources and Bioprocessing. 2024, 11, 79.

4.      Tong Shi, Xinxiao Sun, Qipeng Yuan, Jia Wang, Xiaolin Shen*. Exploring the role of flavin-dependent monooxygenases in the biosynthesis of aromatic compounds. Biotechnology for Biofuels and Bioproducts. 2024, 17, 46.

5.  Xiaolin Shen1, Xiaotian Jiang1, Xinxiao Sun, Qipeng Yuan, Jia Wang*. Identifying and charactering a 4-aminobutyryl-CoA ligase for the production of butyrolactam. Journal of Biotechnology. 2024, 382, 21-27.

6.      Ning An, Shubin Zhou, Xin Chen, Jia Wang, Xinxiao Sun, Xiaolin Shen*, Qipeng Yuan*. High-yield production of β-arbutin by identifying and eliminating byproducts formation. Applied Microbiology and Biotechnology. 2023, 107, 6193-6204.

7.      Zheng Yu, Wenna Li, Chang Ge, Xinxiao Sun, Jia Wang, Xiaolin Shen*, Qipeng Yuan*. Functional expansion of the natural inorganic phosphorus starvation response system in Escherichia coli. Biotechnology Advances, 2023, 108154.

8.      Ning An, Chong Xie, Shubin Zhou, Jia Wang, Xinxiao Sun, Yajun Yan, Xiaolin Shen*, Qipeng Yuan*. Establishing a growth-coupled mechanism for high-yield production of β-arbutin from glycerol in Escherichia coli. Bioresource Technology, 2023, 369, 128491.

9.      Xiaolin Shen, Hongchao Xu, Tong Wang, Ruihua Zhang, Xinxiao Sun, Qipeng Yuan*, Jia Wang*. Rational protein engineering of a ketoacids decarboxylase for efficient production of 1, 2, 4-butanetriol from arabinose. Biotechnology for Biofuels and Bioproducts, 2023, 16,172. 

10.   Zhao Zhou1, Xiangyan Zhang, Jun Wu, Xianglai Li, Wenna Li, Xinxiao Sun, Jia Wang, Yajun Yan, Xiaolin Shen*, Qipeng Yuan*. Targeting cofactors regeneration in methylation and hydroxylation for high level production of Ferulic acid. Metabolic Engineering, 2022, 73, 247-255. 

11.   Xiaolin Shen1, Xin Chen1, Jian Wang, Xinxiao Sun, Sifan Dong, Yang Li, Yajun Yan, Jia Wang, Qipeng Yuan. Design and construction of an artificial pathway for biosynthesis of acetaminophen in Escherichia coli. Metabolic Engineering, 2021, 68, 26-33. 


Awards

Patent

Honor Reward

Admissions Information