IntroductionDr. Shen mainly focus on the research of nano drug diagnosis and treatment system, vaccine carrier adjuvant, and highly sensitive detection system. She has presided over and participated a number of the National Natural Science Foundation of China, the National Basic Research Program of China under Grant and other related projects in the field of biomedical materials. She is currently a member of Polymer Division, Chinese Chemical Society, Chinese Society for Biomaterials and Beijing Society Biomedical Engineering. In the field of nanobiomaterials, she has published more than 30 SCI papers, the papers published in ACS Nano, Small, ACS Appl. Mater. Interfaces, Acta Biomaterialia and other internationally renowned journals. Applied for 9 patents and authorized patents 5. EducationWork ExperienceSocial PositionSocial ActivitiesResearch1. Synthesis of biomedical polymers and construction of nanostructured particles 2. Research on integrated disease diagnosis and treatment system 3. Construction of novel vaccine adjuvants 4. Research on immune detection system Teaching1. Pharmaceutical Process Security and Environmental Evaluaiton 2. Biomedical Engineering Experiment 3. Molecular Diagnosis PostgraduatesFundingVertical ProjectHorizontal ProjectPublications1. Huimin Li, Pengju Li, Jiarui Zhang, Ziyi Lin, Lintao Bai, and Heyun Shen*, Applications of nanotheranostic in the second near-infrared window in bioimaging and cancer treatment, Nanoscale, DOI: 10.1039/D4NR03058C. 2. Yuxuan Li, # Wenxin Li, # Yian Liu, Jiahui Liu, Xinru Yuan, Jiarui Zhang, Heyun Shen*, Defect-rich platinum–zinc oxide heterojunction as a potent ROS amplifier for synergistic sono-catalytic therapy, Acta Biomaterialia, 2023, 171, 543-552. 3. Jiarui Zhang, # Yian Liu, # Lintao Bai, Gan Gao, Yuxuan Li, Heyun Shen*, pH Responsive Poly(Amino Acid) Nanoparticles As Potent Carrier Adjuvants For Enhancing Cellular Immunity, Macromol. Biosci., 2023, 2200520. DOI: 10.1002/mabi.202200520. 4. Meijun Zhao, # Yuxuan Li, # Yian Liu, Lintao Bai, Junjie Ma, Mei Ren, Jiahui Liu, Heyun Shen*, Single Gold Nanostars Achieve Inherent Cascade Catalytic and Near-Infrared Photothermal Activities for Efficient Tumor Therapy. Bioconjugate Chem., 2022, 33, 1934. 5. Xueting Pan,# Pengju Li,#Lintao Bai, Junjie Ma, Shanshan Li, Fengrong Zhang, Shuang Liu, Qingyuan Wu,Heyun Shen*, Huiyu Liu*, Biodegradable Nanocomposite with Dual Cell-Tissue Penetration for Deep Tumor Chemo-Phototherapy.Small, 2020, 16(22), 2000809. 6. Xuewei Wang, Hongyu Wang, Jinlong Tang, Shihui Wang, Dongjian Shi,Heyun Shen*, Poly(amino acid) Multilayers Modified Dendritic Mesoporous Silica Nanoparticles Achieved Effective Enzyme Stability for Ultrasensitive Immunoassay. ACS Appl. Mater. Interfaces, 2020, 12(34), 37906. 7. Lintao Bai, # Mingkun Wang, # Lin Zhang, Meijun Zhao, Mei Ren, Lirong Zheng, Ming Lei, Heyun Shen*, Poly(amino acid) Coordination Nanoparticle as a Potent Sonosensitizer for Cancer Therapy,ACS Appl. Bio Mater., 2021, 4(1), 881. 8. Junjie Ma,# Pengju Li,# Weiwei Wang, Shunhao Wang, Xueting Pan, Fengrong Zhang, Shanshan Li, Shuang Liu, Hongyu Wang, Gan Gao, Bolong Xu, Qipeng Yuan, Heyun Shen*, Huiyu Liu*, Biodegradable Poly(amino acid)-Gold-Magnetic Complex with Efficient Endocytosis for Multimodal Imaging-Guided Chemo-Photothermal Therapy.ACS Nano, 2018, 12(9), 9022-9032. 9. Heyun Shen, Takami Akagi, Mitsuru Akashi*, Polyampholyte nanoparticles prepared by self-complexation of cationized poly (g-glutamic acid) for protein carriers. Macromol. Biosci.,2012, 12(8), 1100-1105. 10. Heyun Shen, Junji Watanabe, Mitsuru Akashi*, Polyelectrolyte multilayers-modified polystyrene plate improves conventional immunoassay: full covering of the blocking reagent. Anal. Chem., 2009, 81(16), 6923-6928. AwardsPatentHonor RewardAdmissions Information |