Niekaili头像

Niekaili

Associate professor

Research direction:

Education:

10 Access

  • Email: niekl@buct.edu.cn
  • Office :
  • Introduction
  • Research
  • Teaching
  • Funding
  • Publications
  • Awards
  • Honor Reward
  • Admission

Introduction

Kaili Nie

Affiliation: Beijing Key Laboratory of Bioprocess, National Energy R&D Center for Biorefinery, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China

Email: niekl@mail.buct.edu.cn

Homepage: https://life.buct.edu.cn/2019/1031/c709a5620/page.htm

Research Interests: Enzyme, Biocatalysis, Enzyme engineering, Directed evolution, Rational design, Metabolic engineering.


Education

Work Experience

Social Position

Social Activities

Research

Research Interests: Enzyme, Biocatalysis, Enzyme engineering, Directed evolution, Rational design, Metabolic engineering.


Teaching

Production Practice: This course organizes students to participate in actual production and labor in one or several specific workshops of a biotechnology company, allowing them to understand the structure, work content, key management points, production technology, equipment management, and quality control of various departments related to production. From this course, the students would learn to apply the knowledge learn from the university to solve the problems in the factory. It will help students to further understand the theoretical knowledge they have learned, and the relationship of the knowledge and the production management. The course also would cultivate their ability to observe, analyze and solve the production process and engineering problems. At the same time, it would helpful for students to prepare for the professional work after graduation.

  • Cognition Practice：Students in this course will understand the establishment and work content of various departments in the biotechnology factory, including the factory’s management, production processes, equipment, and quality control. It will help students further understand the theoretical knowledge they have learned and the relationship between that knowledge and production management. The course would also cultivate their ability to observe, analyze, and solve problems related to production processes and engineering. At the same time, it will be helpful for students in preparing for their subsequent professional studies.

Introduction to Bioengineering Process Design：The course mainly deals with biochemical plants design, and it aims to cultivate the basic ability of process design. The course covers the basics of process design, material and energy balance, equipment selection, cost estimation, safety, pollution prevention and its abatement. 

Bioengineering Process Design：From this course, the students would practice the  technique of biochemical process design. The main contents include the process of material and energy balance, equipment selection, cost estimation, safety, and pollution prevention for a biochemical factory design. 




Postgraduates

Funding

The investigation was financially supported by National key R&D program of China, National Natural Science Foundation of China. 


Vertical Project

Horizontal Project

Publications

  The evolution of cutinase Est1 based on the clustering strategy and its application for commercial PET bottles degradation，Journal of Environmental Management, 2024, 3468: 122217

•    The enhancement of waste PET particles enzymatic degradation with a rotating packed bed reactor, Journal of Cleaner Production, 2024, 434: 140088

•    Reaction-separation coupling process to purify α-linolenic acid based on the hydratase catalytic kinetics differentiation of flaxseed oil fatty acids, Industrial Crops & Products, 2024, 210: 118046

•    Biocatalytic Cascade of Sebacic Acid Production with in situ Co-Factor Regeneration Enabled by Engineering of an Alcohol Dehydrogenase, Catalysts, 2022, 12: 1318

•    One-step synthesis of 4‐octyl itaconate through the structure control of lipase， Journal of Organic Chemistry, 2021, 86: 7895-7903.

•    The conversion of linoleic acid into hydroxytetrahydrofuran-structured bio-lubricant，Journal of Environmental Management, 2021, 291: 112692.

•    Aspergillus niger fermentation residues application to produce biochar for the anode of lithium-ion batteries, Journal of Environmental Management, 2023, 346 : 118985

•    Modification and synthesis of low pour point plant-based lubricants with ionic liquid catalysis，Renewable Energy, 2020, 153: 1320-1329.

•    Synthesis of low pour point bio-aviation fuel from renewable abietic acid，Renewable Energy, 2020, 155: 1042-1050.

•    The highly-stable immobilization of enzymes on a waste mycelium carrier，Journal of Environmental Management, 2020, 271: 111032.

•    β-cyclodextrin as an additive to improve the thermostability of Yarrowia lipolytica Lipase 2: Experimental and simulation insights，Journal of the Taiwan Institute of Chemical Engineers, 2017, 70: 49-55.

•    Sugar-improved enzymatic synthesis of biodiesel with Yarrowia lipolytica Lipase 2, Energy & Fuels, 2017, 31(6): 6248-6256.

•    Chemo-enzymatic epoxidation of Sapindus mukurossi fatty acids catalyzed with Candida sp. 99-125 lipase in a solvent-free system, Industrial Crops and Products, 2017, 98: 10-18.

 


Awards

Patent

Honor Reward

Admissions Information