IntroductionGuofeng Li, an associate professor and master's supervisor at the School of Life Science and Technology, Beijing University of Chemical Technology. His team focuses on using polyamino acid biomimetic nanoparticles to remove drug-resistant bacteria. He presides over general projects of the National Natural Science Foundation of China, youth fund projects, postdoctoral projects, joint projects of Beihua-China-Japan Transformation Center and enterprise cooperation projects. He has published more than 40 papers in academic journals such as Adv. Mater., ACS Nano, Nano Today, Biomacromolecules, ACS Appl. Mater. Interfaces, J. Mater. Chem B, Colloids Surf., B, etc., and has been authorized six invention patents. Academic part-time job: member of the organizing committee of the Antimicrobial Science and Technology Forum. EducationWork ExperienceSocial PositionSocial ActivitiesResearchThe research interest of the group is biomedical materials, focusing on poly(amino acid)-based nanoparticles (PAA NPs) for killing stubborn bacteria, such asintracellular bacteria, persistent bacteria and biofilm. TeachingPostgraduatesFundingThe National Natural Science Foundation of China (22275013, 22005020) and the Joint Project of BRCBC (Biomedical Translational Engineering Research Center of BUCTCJFH, XK2023–16) Vertical ProjectHorizontal ProjectPublications(1) Feng Wenli; Li Guofeng*; Kang Xiaoxu; Wang Ruibai; Liu Fang; Zhao Dongdong; Li Haofei; Bu Fanqiang; Yu Yingjie; Moriarty Thomas Fintan; Ren Qun; Wang Xing*. Cascade-targeting poly(amino acid) nanoparticles eliminate intracellular bacteria via on-site antibiotic delivery. Advanced Materials, 2022, 2109789. (2) Feng Wenli; Chittò Marco; Xie Wensheng; Ren Qun; Liu Fang; Kang Xiaoxu; Zhao Dongdong; Li Guofeng*; Moriarty Thomas Fintan*; Wang Xing*. Poly(d-amino acid) Nanoparticles Target Staphylococcal Growth and Biofilm Disassembly by Interfering with Peptidoglycan Synthesis. ACS Nano, 2024, 18, 8017. (3) Bu Fanqiang; Liu Mengnan; Zhao Wangtao; Liu Fang; Xie Wensheng; Li Guofeng*; Wang Xing*. Programmed degradable core-shell nanoparticles eradicate mature biofilm via precise in-situ phototherapy. Nano Today, 2024, 58, 102449. (4) Kang Xiaoxu; Yang Xuankun; Bu Fanqiang; Feng Wenli; Liu Fang; Xie Wensheng; Li Guofeng*; Wang Xing*. GSH/pH Cascade-Responsive Nanoparticles Eliminate Methicillin-Resistant Staphylococcus aureus Biofilm via Synergistic Photo-Chemo Therapy. ACS Applied Materials & Interfaces, 2024, 16, 3202. (5) Zhao Dongdong; Feng Wenli; Kang Xiaoxu; Li Haofei; Liu Fang; Zheng Weitao; Li Guofeng*; Wang Xing*. Dual-targeted poly(amino acid) nanoparticles deliver drug combinations on-site: an intracellular synergistic strategy to eliminate intracellular bacteria. Journal of Materials Chemistry B, 2023, 11, 2958. AwardsPatentHonor RewardAdmissions Information |