Fengyue

1. Li Y*, Guan L, Becher I, Makarova K, Cao X, Hareendranath S, Guan J, Stein F, Yang S, Boergel A, Lapouge K, Remans K, Agard D, Savitski M, Typas A, Koonin E, Feng Y*, Bondy-Denomy J*. Jumbo phage killer immune system targets early infection of nucleus-forming phages. Cell. 2025, 188(8):2127-2140.e21.

2. Li D, Xiao Y, Fedorova I, Xiong W, Wang Y, Liu X, Huiting E, Ren J, Gao Z, Zhao X, Cao X, Zhang Y, Bondy-Denomy J*, Feng Y*. Single phage proteins sequester signals from TIR and cGAS-like enzymes. Nature. 2024, 635(8039):719-727.

3. Zhang L, Wang H, Zeng J, Cao X, Gao Z, Liu Z, Li F, Wang J, Zhang Y*, Yang M*, Feng Y*. Cas1 mediates the interference stage in a phage-encoded CRISPR–Cas system. Nature Chemical Biology. 2024. doi: 10.1038/s41589-024-01659-5.

4. Zhang Y*, Feng Y*. A broad anti-anti-CRISPR strategy. Nature Chemical Biology. 2024. doi: 10.1038/s41589-024-01743-w

5. Cao X, Xiao Y, Huiting E, Cao X, Li D, Ren J, Fedorova I, Wang H, Guan L, Wang Y, Li L, Bondy-Denomy J*, Feng Y*. Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides. Molecular Cell. 2024, 84(2): 375-385.e7.

6. Huiting E, Cao X, Ren J, Athukoralage J, Luo Z, Silas S, An N, Carion H, Zhou Y, Fraser J, Feng Y*, Bondy-Denomy J*. Bacteriophages inhibit and evade cGAS-like immune function in bacteria. Cell. 2023, 186(4): 864-876. e821.

7. Liu X, Zhang L*, Wang H, Xiu Y, Huang L, Gao Z, Li N, Li F, Xiong W, Gao T, Zhang Y, Yang M*, Feng Y*. Target RNA activates the protease activity of Craspase to confer antiviral defense. Molecular Cell. 2022, 82(23): 4503-4518.e4508.

8. Xie Y, Zhang L, Gao Z, Yin P, Wang H, Li H, Chen Z, Zhang Y, Yang M, Feng Y*. AcrIF5 specifically targets DNA-bound CRISPR-Cas Surveillance Complex for inhibition. Nature Chemical Biology. 2022, 18(6):670-677.

9. Yang L, Zhang L, Yin P, Ding H, Xiao Y, Zeng J, Wang W, Zhou H, Wang Q, Zhang Y, Chen Z, Yang M, Feng Y*. Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nature Communications. 2022, 13(1):1931.

10. Niu Y, Yang L, Gao T, Dong C, Zhang B, Yin P, Hopp A-K, Li D, Gan R, Wang H, Liu X, Cao X, Xie Y, Meng X, Deng H, Zhang X, Ren J, Hottiger M, Chen Z*, Zhang Y*, Liu X*, Feng Y*. A type I-F anti-CRISPR protein inhibits the CRISPR-Cas Surveillance Complex by ADP-ribosylation. Molecular Cell. 2020, 80(3):512-524

11. Mu Y, Wang Y, Huang Y, Li D, Han Y, Chang M, Fu J, Xie Y, Ren J, Wang H, Zhang Y, Luo Z, Feng Y*. Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC. Nature Communications. 2020, 11(1):1774.

12. Dong Y, Mu Y, Xie Y, Zhang Y, Han Y, Zhou Y, Wang W, Liu Z, Wu M, Wang H, Pan M, Xu N, Xu C, Yang M, Fan S, Deng H, Tan T, Liu X, Liu L, Li J, Wang J, Fang X & Feng Y*. Structural basis of ubiquitin modification by the Legionella effector SdeA. Nature. 2018, 557(7707):674-678 (highlighted in News and Views)

13. Wang W, Li J, Sun Q, Yu X, Zhang W, Jia N, An C, Li Y, Dong Y, Han F, Chang N, Liu X, Zhu Z, Yu Y, Fan S, Yang M, Luo S, Gao H*, Feng Y*. Structural insights into the coordination of plastid division by the ARC6-PDV2 complex. Nature Plants. 2017, 3:17011. (Selected as Hero image article, highlighted in News and Views and commented by Editorial in Nature Plants)