Chenbiqiang头像

Chenbiqiang

Research Fellow

Research direction: Industrial enzyme catalysis

Education:

  • Department: College of Life Science and Technology
  • ORCID:
  • DBLP:

10 Access

  • Email: chenbq@mail.bcut.edu.cn
  • Office :
  • Introduction
  • Research
  • Teaching
  • Funding
  • Publications
  • Awards
  • Honor Reward
  • Admission

Introduction

Chen Biqiang, professor, received his Ph.D. in biochemical engineering from Beijing University of Chemical Technology in 2008. He did postdoctoral research at the Institute of Biochemical Engineering, Department of Chemical Engineering, Tsinghua University from 2009 to 2010. He has been working at Beijing University of Chemical Technology since 2010. He has been engaged in research in the field of industrial enzyme catalysis for a long time. As the project leader, he has undertaken more than 20 projects funded by the National Natural Science Foundation, the National Key R&D Program, 973 and 863 projects, and corporate horizontal projects. In recent years, he has published more than 50 SCI papers and applied for 20 patents. He won 1 second prize of the National Technological Invention Award in 2008, 1 first prize of Sinopec Technological Invention Award, and 1 second prize of Beijing Science and Technology Progress Award. He won the Youth Outstanding Paper Award of the Enzyme Engineering Professional Committee of the Chinese Society of Microbiology in 2011. In 2010, he won the Outstanding Contribution Award of the 10,000 Scientific Problems of the Ministry of Education.

Education

Work Experience

Social Position

Social Activities

Research

1、Industrial enzyme development and application

2、Enzyme molecule design and modification based on machine learning

3、Enzyme immobilization technology

4、Biocatalytic synthesis of oil and fat chemicals


Teaching

Undergraduate Programs：

Enzyme and protein engineering

Graduate Programs：

Biochemical reaction engineering



Postgraduates

Funding

Vertical Project

Horizontal Project

Publications

1.     Xiaowei Shen，Shiding Zhang，Jianyu Long，Changjing Chen，Meng Wang，Ziheng Cui*，Biqiang Chen*，Tianwei Tan. A Highly Sensitive Model Based on Graph Neural Networks for Enzyme Key Catalytic Residue Prediction[J]. Journal of Chemical Information and Modeling, 2023, 63(14): 4277-4290

2.     Shiming Huang, Di Cai, Chaofeng Shao,  Changwei Zhang, Junhui Zhou, Ziheng Cui, Tianqi He, Changjing Chen* Biqiang Chen* and  Tianwei Tan，Depolymerization of post-consumer PET bottles with engineered cutinase 1 from Thermobifida cellulosilytica[J]. Green Chemistry, 2022, 24(15): 5998-6007

3.     Sun Jiaqi，Yu Senshen，Cui,Ziheng，Hu Lin，Sun Bowen，Chen, Biqiang*. Synthesis, characterization, and photocatalytic antibacterial activities of porous Ce-doped TiO2 microspheres using pine pollen as novel biotemplates[J]. Journal of Materials Science, 2022, 57(32): 15276-15297.

4.     Zixuan Zhang，Di Cai，Chaofeng Shao，Changjing Chen*，Biqiang Chen*. Purification of high-temperature resistant polyethylene terephthalate (PET) hydrolase by simple heating protocol[J]. Process Biochemistry, 2022, 114: 42-51.

5.     Shiding Zhang，Senshen Yu，Meng Wang，Ziheng Cui*，Biqiang Chen*，Tianwei Tan. Enzyme self-aggregation in supramolecular self-assembly of glucose oxidase and catalase: Insight from molecular dynamics simulation based on coarse-grained method[J]. Chemical Physics, 2022, 552: 111366.

6.     Junhui Zhou，Xinyu Tian，Qian Yang，Changjing Chen，Ziheng Cui，Yu Ji ，Ulrich Schwaneberg，Biqiang Chen*，Tianwei Tan*. Three multi-enzyme cascade pathways for conversion of C1 to C2/C4 compounds[J]. Chem Catalysis, 2022.

7.     Senshen Yu, Shiding Zhang, Kunning Li, Qian Yang, Meng Wang, Di Cai*, Tianwei Tan, and Biqiang Chen*. Furfuryl Alcohol Production with High Selectivity by a Novel Visible-Light Driven Biocatalysis Process[J]. ACS Sustainable Chemistry & Engineering, 2020, 8(42): 15980-15988.

8.     Caixia Cui, Yunming Fang*, Biqiang Chen*, and Tianwei Tan. Glucose oxidation performance is improved by the use of a supramolecular self-assembly of glucose oxidase and catalase[J]. Catalysis Science & Technology, 2019, 9(2): 477-482.

9.     Kai WANG, Zihe Liu, Biqiang Chen, Meng Wang, Yang Zhang, Haoran Bi, Yali Zhou, Yiying Huo, Tianwei Tan. Microbial utilization of carbon dioxide to synthesize fuels and chemicals——third-generation biorefineries[J]. Synthetic Biology Journal, 2020, 1(1): 60.

10.   Wei Zhang, Hairui Ji, Yanliang Song, Sen Ma, Wei Xiong, Changjing Chen, Biqiang Chen*, Xu Zhang*, Green preparation of branched biolubricant by chemically modifying waste cooking oil with lipase and ionic liquid[J]. Journal of Cleaner Production, 2020, 274: 122918.

11.   Meng Wang, Xiaojun Tian, Biqiang Chen, Hailong Lin*, Guojun Yue. Future Modes of Fuel Bioethanol Industry[J]. Strategic Study of Chinese Academy of Engineering, 2020, 22(2): 47-54.

12.   Wei Zhang, Jinquan Wu, Senshen Yu, Ying Shen, Yamin Wu, Biqiang Chen, Kaili Nie*, Xu Zhang*. Modification and synthesis of low pour point plant-based lubricants with ionic liquid catalysis[J]. Renewable Energy, 2020, 153: 1320-1329.

13.   Houchao Shan, Shufeng Li*, Xinmiao Zhang, Fanning Meng, YanZhuang, Zhihao Si, Di Cai, Biqiang Chen, Peiyong Qin*. Molecular dynamics simulation and preparation of vinyl modified polydimethylsiloxane membrane for pervaporation recovery of furfural[J]. Separation and Purification Technology, 2021, 258: 118006.

14.   Wenlong Zhu, Miaomiao Gao, Biqiang Chen, Tianwei Tan, Hui Cao*, Luo Liu*. The Synthesis of Mannose-6-Phosphate Using Polyphosphate-Dependent Mannose Kinase[J]. Catalysts, 2019, 9(3): 250.

15.   Qingqing Jia, Xingning Teng, Senshen Yu, Zhihao Si, Guozhen Li, Mingyuan Zhou, Di Cai*, Peiyong Qin, Biqiang Chen. Production of furfural from xylose and hemicelluloses using tin-loaded sulfonated diatomite as solid acid catalyst in biphasic system[J]. Bioresource Technology Reports, 2019, 6: 145-151.

16.   Senshen Yu, Pengfei Lv, Pan Xue, Kai Wang, QianYang, Junhui Zhou, Meng Wang, Ling Wang*, Biqiang Chen*, Tianwei Tan*. Light-driven enzymatic nanosystem for highly selective production of formic acid from CO2[J]. Chemical Engineering Journal, 2021, 420: 127649.

17.   Junhui Zhou, Senshen Yu, Helong Kang, Rui He, Yuxin Ning, Yingyue Yu, Meng Wang*, Biqiang Chen*. Construction of multi-enzyme cascade biomimetic carbon sequestration system based on photocatalytic coenzyme NADH regeneration[J]. Renewable Energy, 2020, 156: 107-116.

18.   Ziheng Cui,Shiding Zhang,Shengyu Zhang, Biqiang Chen, Yushan Zhu*, TianweiTan*. Green biomanufacturing promoted by automatic retrobiosynthesis planning and computational enzyme design[J]. Chinese Journal of Chemical Engineering, 2021.

19.   Xiaonan Zhang, Wenxuan Shao, Biqiang Chen*, Meng Wang*. Cross-linking of carbonic anhydrase and formate dehydrogenase based on amino acid specific recognition: Conversion of carbon dioxide to formic acid[J]. Enzyme and Microbial Technology, 2021, 146: 109763.

20.   Yang Zhang, Jing Yu, Yilu Wu, Mingda Li, Yuxuan Zhao, Haowen Zhu, Changjing Chen,Meng Wang, Biqiang Chen, TianweiTan*. Efficient production of chemicals from microorganism by metabolic engineering and synthetic biology[J]. Chinese Journal of Chemical Engineering, 2021, 30: 14-28.

 


Awards

1. Second  Prize  of  National  Technology  Invention Award  for  Green  Synthesis Process of Chemicals Using Lipase as Catalyst in 2008.

2. First Prize of SINOPEC Technological  Invention Award for Green Chemical Synthesis Process Using Lipase as Catalyst in 2005.

3. 2010 Outstanding Contribution Award of 10,000 Scientific Problems, Ministry of Education, China.

4. 2011  Awarded  Young  Excellent  Paper  Award  by  Enzyme  Engineering Committee of Chinese Society of Microbiology.

5. Selected by Beijing Youth Talent Program in 2013

6. Beijing Science and Technology Rising Star Program, 2016

Patent

Honor Reward

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